Hormones & health basics

Hormones & health basics

Start here if you want the foundations: what TRT is, what “normal” monitoring looks like, what side effects usually mean, and which lifestyle levers move outcomes the most.

Foundation first. Optimisation later.

Category: Hormones & health basics Level: Beginner Reading time: ~5 minutes Last updated: 19 Dec 2025

Start here: hormone basics that prevent dumb mistakes

This is the foundation layer: how TRT works, what “side effects” usually mean, what to track, and what to fix before you touch dose.

New to labs? Use the Bloodwork guide pathway to understand what to test and how to interpret trends before you start “optimising.”

Core hormone basics journey

Follow these in order if you’re new to TRT/peptides or want a clean “first principles” reset.

  1. What is TRT? – what it is, what it isn’t, and what “replacement” should look like in real life.
  2. Common side effects & monitoring – the usual issues (water retention, acne, mood, libido swings), and what to check before panic moves.
  3. Lifestyle factors that move the needle – sleep, stress, training load, alcohol, body fat, and why they can make your numbers look “off.”
Rule

If you’re changing dose to fix a lifestyle problem, you’re doing it backwards.

Specific topics you might be looking for

TRT fundamentals

For people deciding whether TRT makes sense and what “good TRT” looks like.

Symptoms, side effects, guardrails

When things feel “off,” this is the triage lane.

Lifestyle levers before dose changes

The boring stuff that often fixes the problem faster than changing dose.

Search within hormone basics

Type a keyword (e.g. “libido”, “sleep”, “estradiol”, “SHBG”, “acne”) and search across hormone basics guides.

General information only

These guides are educational. They do not interpret your personal results or replace medical care.